Best hospitals in the US for endometriosis: A clinical care comparison

People researching the best hospitals in the US for endometriosis are typically looking for specialized teams that can address pelvic pain, infertility, bowel or bladder symptoms, and recurrent disease. The hospitals and programs below are presented as examples identified in the supplied research, not as a universal ranking, because the appropriate center depends on disease location, treatment history, fertility goals, and access to coordinated care.

How hospitals should be compared

A meaningful comparison should focus on endometriosis-specific experience rather than a hospital's overall reputation alone. Useful indicators include minimally invasive gynecologic surgery, complex excision capability, reproductive endocrinology, pelvic pain management, pelvic floor therapy, and access to colorectal or urologic specialists when disease extends beyond the reproductive organs. An evidence-based patient guide also emphasizes communication, individualized treatment goals, and multidisciplinary support when bowel, bladder, ureter, diaphragm, or pelvic nerve involvement is suspected. 1

Hospitals with nationally recognized capabilities

Mayo Clinic in Rochester is identified in the supplied research as consistently highly ranked nationally for gynecology and as a provider of complex endometriosis excision surgery. Cleveland Clinic is also a major reference point: its endometriosis services use a multidisciplinary model that combines surgery with pain management and pelvic floor physical therapy. Separately, Cleveland Clinic reported a 2026-2027 U.S. News Honor Roll position, national ranking in 13 of 14 specialties, and an Obstetrics and Gynecology ranking of 18. 2 3

• Mayo Clinic, Rochester, Minnesota: complex gynecologic and surgical expertise.
• Cleveland Clinic, Cleveland, Ohio: multidisciplinary endometriosis-related services and broad specialty infrastructure.
• Johns Hopkins Hospital, Baltimore, Maryland: specialized care for deep infiltrating disease and minimally invasive laparoscopic surgery.

Specialized centers and formal designations

UF Health became the sixth Center of Excellence in Complex Endometriosis Care worldwide in 2025, according to the University of Florida Health report. The same report states that only four such facilities existed in the United States at that time, and that UF surgeons Nash Moawad and Amira Quevedo were recognized by the Surgical Review Corporation as surgeons of excellence. The program describes complex cases involving overlapping conditions such as irritable bowel syndrome, polycystic ovary syndrome, anxiety, and depression. 4

Hoag in California was reported as the first hospital in California and the first in the western United States to receive the Surgical Review Corporation's Center of Excellence in Multidisciplinary Endometriosis Care designation. Its program brings together gynecology, colorectal surgery, gastroenterology, pain management, and related specialties. The report also identifies Marc Winter as a surgeon holding both multidisciplinary endometriosis care and robotic surgery designations. 5

Regional programs for surgery and fertility goals

Brigham and Women's Hospital in Boston operates a Center for Endometriosis described in the research as emphasizing integrated care and fertility preservation. UCLA Health in Los Angeles uses robotic-assisted laparoscopic surgery, with an emphasis on removing disease while restoring anatomy and limiting recovery demands. These approaches may be relevant to patients comparing surgical programs, but the presence of robotic equipment alone does not establish that surgery is necessary or that one technique is appropriate for every case. 6 7

West Coast and academic referral options

Cedars-Sinai in Los Angeles is identified as having specialized endometriosis surgical teams and comprehensive patient support services. UCSF provides medical and surgical care alongside research, with attention to quality of life and longer-term symptom management. Stanford Health Care is described as offering specialized diagnostic and surgical programs for complex cases involving the bowel, bladder, or diaphragm. These academic and referral settings may be useful when symptoms involve several organ systems or when previous treatment has not resolved the condition. 8 9 10

• Cedars-Sinai: specialized surgical teams and support services.
• UCSF: clinical care, surgical treatment, research, and quality-of-life considerations.
• Stanford Health Care: complex extra-pelvic disease involving organs such as the bowel, bladder, or diaphragm.

What treatment planning may involve

Endometriosis care can include pain management, hormonal therapy, fertility services, surgery, or combinations of these approaches. MUSC Women's Health describes advanced training in both traditional laparoscopic and robotic techniques for complex conditions, while its patient account illustrates how pelvic pain, heavy bleeding, fatigue, and bladder symptoms can be misattributed to urinary or gastrointestinal disorders. Mount Sinai is identified as offering specialized endometriosis and chronic pelvic pain services, including advanced diagnostic imaging and clinical-trial access. 11 12

Patients should ask whether a proposed operation is intended to remove visible disease, treat an endometrioma, preserve ovarian tissue, address bowel or urinary involvement, or support fertility planning. The supplied research also describes dedicated centers using meticulous excision and nerve-sparing or fertility-sparing principles, but these descriptions come from provider sources and should be discussed with an independent clinician in the context of individual risks. No surgical method guarantees symptom resolution or prevents recurrence. 13

Risks, eligibility, and practical limitations

A hospital's designation or national specialty ranking does not guarantee eligibility, insurance coverage, appointment availability, or a particular outcome. Complex surgery can require coordination among gynecologic, colorectal, urologic, gastrointestinal, pain, fertility, and mental-health professionals. Travel, postoperative monitoring, prior operations, medical comorbidities, and the distinction between suspected and confirmed disease can affect whether a program accepts a referral or recommends surgery. 1 4

Before comparing hospitals, a patient can organize imaging reports, operative notes, pathology, medication history, prior hormonal treatments, fertility priorities, and the specific symptoms affecting daily life. Questions should cover the surgeon's experience with disease in the relevant organs, non-surgical alternatives, complication planning, recovery support, recurrence monitoring, and how fertility concerns will be handled. This process provides a more reliable basis for choosing among the recognized programs than a generalized list of the nation's most prominent hospitals.

Sources

1. Acibadem International, Evidence-Based Patient Guide
2. Mayo Clinic and U.S. News & World Report, Gynecology information
3. Cleveland Clinic, Endometriosis services and 2026-2027 hospital report
4. UF Health, Center of Excellence in Complex Endometriosis Care
5. Hoag, Multidisciplinary Endometriosis Care designation report
6. Brigham and Women's Hospital, Center for Endometriosis
7. UCLA Health, Endometriosis services
8. Cedars-Sinai, Endometriosis specialty care
9. UCSF Health, Endometriosis care and research
10. Stanford Health Care, Endometriosis services
11. MUSC Women's Health, Expert endometriosis care
12. Mount Sinai, Endometriosis and chronic pelvic pain services
13. Endometriosis Surgical Specialists International, Fertility-sparing surgery information